Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTQOVYA)

• DTT Name: C-X-C motif chemokine 10 (CXCL10) DTT Info
• Gene Name: CXCL10

Molecule-Related Drug & Molecule List

6 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Anti-IP10	DMVRNAO	Crohn disease	DD70	Phase 2	[1]
BMS-936557	DMUTS1W	Immune System disease	4A01-4B41	Phase 2	[1]
JT02	DMXTKCR	Inflammatory bowel disease	DD72	Phase 2	[2]
MDX-1100	DM0EZWI	Crohn disease	DD70	Phase 2	[3]
NI-0801	DMRQUH4	Autoimmune diabetes	5A10	Phase 2	[4]
NG-641	DMITVHM	Solid tumour/cancer	2A00-2F9Z	Phase 1	[5]

1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
N-Methylleucine	DM9AGCV	Discovery agent	N.A.	Investigative	[6]

References

• [1] Anti-IP-10 antibody (BMS-936557) for ulcerative colitis: a phase II randomised study. Gut. 2014 Mar;63(3):442-50.
• [2] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [3] A phase II, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of MDX-1100, a fully human anti-CXCL10 monoclonal antibody, in combination with methotrexate in patients with rheumatoid arthritis. Arthritis Rheum. 2012 Jun;64(6):1730-9.
• [4] Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800029267)
• [5] Clinical pipeline report, company report or official report of PsiOxus Therapeutics.
• [6] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.