General Information of DTT (ID: TTQZW34)

DTT Name Plasmodium Apical membrane protein (Malaria AMA-1) DTT Info
Gene Name Malaria AMA-1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Clinical Trial Drug(s)
3 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
AdCh63 AMA1 DMEGPSW Malaria 1F40-1F45 Phase 1/2 [1]
DNA-Ad DM71BFM Malaria 1F40-1F45 Phase 1/2 [2]
PfAMA-1 DMLDZX1 Malaria 1F40-1F45 Phase 1 [3]
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Molecule Interaction Atlas

References

1 ClinicalTrials.gov (NCT01142765) Study to Assess Efficacy of New Malaria Vaccine Candidates AdCh63 AMA1, MVA AMA1, AdCh63 MSP1, MVA MSP1, AdCh63 ME-TRAP & MVA ME-TRAP. U.S. National Institutes of Health.
2 Sterile immunity to malaria after DNA prime/adenovirus boost immunization is associated with effector memory CD8+T cells targeting AMA1 class I epitopes. PLoS One. 2014 Sep 11;9(9):e106241.
3 Plasmodium falciparum apical membrane antigen 1 (PfAMA-1) is translocated within micronemes along subpellicular microtubules during merozoite devel... J Cell Sci. 2003 Sep 15;116(Pt 18):3825-34.