Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTR9XHZ)

DTT Name	Transforming growth factor beta 1 (TGFB1) DTT Info
Gene Name	TGFB1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Discontinued Drug(s)

Approved Drug(s)

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Pirfenidone	DM6VZFQ	Idiopathic pulmonary fibrosis	CB03.4	Approved	[1]
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7 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
A435	DMJCL7X	Aggressive cancer	2A00-2F9Z	IND submitted	[2]
TG-C	DMLCXPD	Arthritis	FA20	Phase 3	[3]
LY2157299	DMP8HW1	Arteriosclerosis	BD40	Phase 2/3	[4]
Disitertide	DM2QBDS	Macular degeneration	9B78.3	Phase 2	[5]
ABBV-151	DMIQXDJ	Solid tumour/cancer	2A00-2F9Z	Phase 1	[6]
ACE-1334	DMF1OUP	Systemic sclerosis	4A42	Phase 1	[7]
SRK-181	DM0EWMT	Solid tumour/cancer	2A00-2F9Z	Phase 1	[8]
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⏷ Show the Full List of 7 Clinical Trial Drug(s)

1 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Mannose phosphate	DM1LM7D	Lesion	8A00-8C12	Discontinued in Phase 2	[9]
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1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ART-144	DMEVT4I	Osteoarthritis	FA00-FA05	Investigative	[10]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
2	Clinical pipeline report, company report or official report of Klus Pharma
3	Clinical pipeline report, company report or official report of Tissue Gene, Inc.
4	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
5	Perspectives of TGF-beta inhibition in pancreatic and hepatocellular carcinomas. Oncotarget. 2014 January; 5(1): 78-94.
6	Clinical pipeline report, company report or official report of AbbVie.
7	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2023. Adis Insight
8	Clinical pipeline report, company report or official report of Scholar Rock.
9	The mannose-6-phosphate analogue, PXS64, inhibits fibrosis via TGF-beta1 pathway in human lung fibroblasts. Immunol Lett. 2015 Jun;165(2):90-101.
10	Pharmaceutical products of TORREYA partners. December 2011.