Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTS5K1M)

• DTT Name: Hepatitis B virus Reverse transcriptase (HBV RT) DTT Info
• Gene Name: HBV RT

Molecule-Related Drug & Molecule List

2 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Adefovir Dipivoxil	DMMAWY1	Hepatitis B virus infection	1E51.0	Approved	[1]
Entecavir	DM7VTQO	Hepatitis B virus infection	1E51.0	Approved	[2]

4 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Clevudine	DMR21Q3	Hepatitis B	1E51	Phase 3	[3]
LB80380	DMJM9LZ	Hepatitis B virus infection	1E51.0	Phase 2b	[4]
MIV-210	DM2NF6X	Hepatitis B virus infection	1E51.0	Phase 2	[5]
Pradefovir	DM1O0DV	Hepatitis virus infection	1E50-1E51	Phase 2	[6]

References

• [1] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
• [2] Effect of hepatitis B virus reverse transcriptase variations on entecavir treatment response. J Infect Dis. 2014 Sep 1;210(5):701-7.
• [3] 2011 Pipeline of Bukwang.
• [4] 2011 Pipeline of LG Life Sciences.
• [5] Emerging antivirals for the treatment of hepatitis B
• [6] DOI: 10.1128/AAC.01566-05