Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTS7LWX)

DTT Name	Bacterial DNA gyrase B (Bact gyrB) DTT Info
Gene Name	Bact gyrB

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

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1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
SPR720	DMJDV0K	Mycobacterium infection	1B10-1B21	Phase 1/2	[1]
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2 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BAY 50-7952	DM743XB	Discovery agent	N.A.	Investigative	[2]
Coumermycin	DMAJNPS	Discovery agent	N.A.	Investigative	[3]
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Molecule Interaction Atlas

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References

1	Advancement of GyrB Inhibitors for Treatment of Infections Caused by Mycobacterium tuberculosis and Non-tuberculous Mycobacteria. ACS Infect Dis. 2020 Jun 12;6(6):1323-1331.
2	seco-Cyclothialidines: new concise synthesis, inhibitory activity toward bacterial and human DNA topoisomerases, and antibacterial properties. J Med Chem. 2001 Feb 15;44(4):619-26.
3	Isolation and characterization of an Escherichia coli strain exhibiting partial tolerance to quinolones. Antimicrob Agents Chemother. 1989 May;33(5):705-9.