General Information of DTT (ID: TTSJ542)

DTT Name Integrin alpha-2 (ITGA2) DTT Info
Gene Name ITGA2

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Clinical Trial Drug(s)
Investigative Drug(s)
1 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
E7820 DMZRXTL Colorectal cancer 2B91.Z Phase 2 [1]
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4 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
3-(3-(benzamido)-5-nitrobenzamido)propanoic acid DMY4VX2 Discovery agent N.A. Investigative [2]
3-(3-(carbamoyl)benzamido)-3-phenylpropanoic acid DM2K51S Discovery agent N.A. Investigative [2]
3-(3-(carbamoyl)benzamido)propanoic acid DM31JAZ Discovery agent N.A. Investigative [2]
MAGGIEMYCIN DMSQL19 Discovery agent N.A. Investigative [3]
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Molecule Interaction Atlas

References

1 Phase I study of E7820, an oral inhibitor of integrin alpha-2 expression with antiangiogenic properties, in patients with advanced malignancies. Clin Cancer Res. 2011 Jan 1;17(1):193-200.
2 Derivatives of 7-amino-1,2,3,4-tetrahydroisoquinoline and isophthalic acids as novel fibrinogen receptor antagonists. Bioorg Med Chem Lett. 2006 Oct 15;16(20):5294-7.
3 Small molecule designed to target metal binding site in the alpha2I domain inhibits integrin function. J Med Chem. 2007 May 31;50(11):2742-6.