Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTT4SY6)

DTT Name	Hepatitis B virus Polymerase (HBV P) DTT Info
Gene Name	HBV P

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Discontinued Drug(s)

Approved Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Telbivudine	DMSWUGE	Hepatitis B virus infection	1E51.0	Approved	[1]
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2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ATI-2173	DMT5QYJ	Hepatitis B	1E51	Phase 2	[2]
NCO-48	DMUSPW5	Hepatitis B virus infection	1E51.0	Phase 1	[3]
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1 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Valtorcitabine	DMXQCBU	Hepatitis virus infection	1E50-1E51	Discontinued in Phase 2	[4]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Nucleos(t)ide analogues for hepatitis B virus: strategies for long-term success. Best Pract Res Clin Gastroenterol. 2008;22(6):1081-92.
2	ATI-2173, a Novel Liver-Targeted Non-Chain-Terminating Nucleotide for Hepatitis B Virus Cure Regimens. Antimicrob Agents Chemother. 2020 Aug 20;64(9):e00836-20.
3	Safety, Tolerability and Pharmacokinetics of NCO-48 Fumarate in Healthy Subjects
4	Prodrugs of nucleoside analogues for improved oral absorption and tissue targeting. J Pharm Sci. 2008 Mar;97(3):1109-34.