Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTUKLBM)

DTT Name Huntingtin (HTT) DTT Info
Gene Name HTT

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
2 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tominersen DM7ERXY Huntington disease 8A01.10 Phase 3 [1]
AMT-130 DM20B90 Huntington disease 8A01.10 Phase 1/2 [2]
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Molecule Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1 Potential disease-modifying therapies for Huntington's disease: lessons learned and future opportunities. Lancet Neurol. 2022 Jul;21(7):645-658.
2 ClinicalTrials.gov (NCT05243017) A Phase Ib/II Study to Explore Safety, Tolerability, and Efficacy Signals of Multiple Ascending Doses of Striatally-Administered rAAV5-miHTT Total Huntingtin Gene (HTT) Lowering Therapy (AMT 130) in Early Manifest Huntington's Disease. U.S.National Institutes of Health.