Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTUMHT8)

• DTT Name: Tyrosine-protein kinase ZAP-70 (ZAP-70) DTT Info
• Gene Name: ZAP70

Molecule-Related Drug & Molecule List

3 Patented Agent(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
US8546370, 102	DMQRO6G	N. A.	N. A.	Patented	[1]
US8546370, 11	DM2K6YU	N. A.	N. A.	Patented	[1]
US8546370, 17	DMGIJZA	N. A.	N. A.	Patented	[1]

2 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
aloisine	DM7HGX8	Discovery agent	N.A.	Investigative	[2]
K00592a	DM1RP5Q	Discovery agent	N.A.	Investigative	[3]

References

• [1] Compounds and compositions as kinase inhibitors. US8546370.
• [2] Identification of binding specificity-determining features in protein families. J Med Chem. 2012 Mar 8;55(5):1926-39.
• [3] Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure-activity relationships of pyrimidine-5-carboxamide derivatives. Bioorg Med Chem. 2005 Aug 15;13(16):4936-51.