Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTVZJ7G)

DTT Name	Cystathionine beta-synthase (CBS) DTT Info
Gene Name	CBS

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

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1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
OT-58	DMWCJ1F	Homocystinuria	5C50.B	Phase 1/2	[1]
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2 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
aminooxyacetic acid	DMHNDTW	Discovery agent	N.A.	Investigative	[2]
Heme	DMGC287	Discovery agent	N.A.	Investigative	[3]
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Molecule Interaction Atlas

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References

1	Classical homocystinuria: From cystathionine beta-synthase deficiency to novel enzyme therapies. Biochimie. 2020 Jun;173:48-56.
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1443).
3	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.