Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTWVL5Q)

DTT Name	Voltage-gated potassium channel Kv7.5 (KCNQ5) DTT Info
Gene Name	KCNQ5

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

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4 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
(S)-N-[1-(3-morpholin-4-yl-phenyl)-ethyl]-3-phenyl-acrylamide	DMGFOQJ	Discovery agent	N.A.	Investigative	[1]
XE991	DMLH1PK	Discovery agent	N.A.	Investigative	[2]
zinc pyrithione	DMF0CRA	Discovery agent	N.A.	Investigative	[3]
[14C]TEA	DM6SFYH	Discovery agent	N.A.	Investigative	[2]
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Molecule Interaction Atlas

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References

1	The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels. Neuropharmacology. 2006 Nov;51(6):1068-77.
2	KCNQ5, a novel potassium channel broadly expressed in brain, mediates M-type currents. J Biol Chem. 2000 Aug 4;275(31):24089-95.
3	Zinc pyrithione-mediated activation of voltage-gated KCNQ potassium channels rescues epileptogenic mutants. Nat Chem Biol. 2007 May;3(5):287-96.