Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTYXPCO)

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Discontinued Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

1 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
INS 316	DMTHMEI	Lung cancer	2C25.0	Discontinued in Phase 3	[1]
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8 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2MeSATP	DMUE0W6	Discovery agent	N.A.	Investigative	[2]
ATPgammaS	DMXHQIN	Discovery agent	N.A.	Investigative	[2]
BzATP	DM37GYA	Discovery agent	N.A.	Investigative	[2]
dATP	DMMXFBJ	Discovery agent	N.A.	Investigative	[2]
NAADP	DM51DW6	Discovery agent	N.A.	Investigative	[3]
NF157	DMGMH8T	Discovery agent	N.A.	Investigative	[4]
NF340	DMPSXR8	Discovery agent	N.A.	Investigative	[5]
NF546	DMPZB31	Discovery agent	N.A.	Investigative	[6]
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⏷ Show the Full List of 8 Investigative Drug(s)

Molecule Interaction Atlas

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References

1	Characterization of a Ca2+ response to both UTP and ATP at human P2Y11 receptors: evidence for agonist-specific signaling. Mol Pharmacol. 2003 Jun;63(6):1356-63.
2	Pharmacological characterization of the human P2Y11 receptor. Br J Pharmacol. 1999 Nov;128(6):1199-206.
3	NAADP+ is an agonist of the human P2Y11 purinergic receptor. Cell Calcium. 2008 Apr;43(4):344-55.
4	Synthesis and structure-activity relationships of suramin-derived P2Y11 receptor antagonists with nanomolar potency. J Med Chem. 2005 Nov 3;48(22):7040-8.
5	Invited Lectures : Overviews Purinergic signalling: past, present and future. Purinergic Signal. 2006 May;2(1):1-324.
6	NF546 [4,4'-(carbonylbis(imino-3,1-phenylene-carbonylimino-3,1-(4-methyl-phenylene)-carbonylimino))-bis(1,3-xylene-alpha,alpha'-diphosphonic acid) tetrasodium salt] is a non-nucleotide P2Y11 agonist and stimulates release of interleukin-8 from human monocyte-derived dendritic cells. J Pharmacol Exp Ther. 2010 Jan;332(1):238-47.