Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTZ8UT4)

• DTT Name: Wilms tumor protein (WT1) DTT Info
• Gene Name: WT1

Molecule-Related Drug & Molecule List

7 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Combined PR1/WT1 vaccine	DMGCTX5	Myeloid leukaemia	2B33.1	Phase 2	[1]
FPI-01	DMXOTMP	Acute myeloid leukaemia	2A60	Phase 2	[2]
WT1 peptide vaccine	DMZ67Q0	leukaemia	2A60-2B33	Phase 2	[3]
WT1-targeted autologous dendritic cell vaccine	DMNFZYE	Acute myeloid leukaemia	2A60	Phase 2	[4]
WT-4869	DM3FIMD	leukaemia	2A60-2B33	Phase 1/2	[5]
GSK-2130579A	DMRXW9P	Acute myeloid leukaemia	2A60	Phase 1	[6]
INNO-305	DMG6S8U	Acute myeloid leukaemia	2A60	Phase 1	[7]

References

• [1] Leukemia-associated antigen-specific T-cell responses following combined PR1 and WT1 peptide vaccination in patients with myeloid malignancies. Blood. 2008 Jan 1;111(1):236-42.
• [2] Clinical pipeline report, company report or official report of Formula Pharmaceuticals.
• [3] Wilms' tumor protein 1 (WT1) peptide vaccination in AML patients: predominant TCR CDR3beta sequence associated with remission in one patient is detectable in other vaccinated patients. Cancer ImmunolImmunother. 2012 Mar;61(3):313-22.
• [4] ClinicalTrials.gov (NCT01686334) Efficacy Study of Dendritic Cell Vaccination in Patients With Acute Myeloid Leukemia in Remission. U.S. National Institutes of Health.
• [5] Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033385)
• [6] Spoilight on personalized medicine. A pharma matters report, Thomson Reuters, 2012.
• [7] Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800023753)