Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTZ963I)

• DTT Name: Monoglyceride lipase (MAGL) DTT Info
• Gene Name: MGLL

Molecule-Related Drug & Molecule List

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ABX-1431	DM9SYVJ	Neuropathic pain	8E43.0	Phase 1	[1]

45 Patented Agent(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Azetidine-benzoxazin-3(4H)-one derivative 1	DMRMED4	N. A.	N. A.	Patented	[2]
Azetidine-benzoxazin-3(4H)-one derivative 2	DMMSPX7	N. A.	N. A.	Patented	[2]
Azetidine-benzoxazin-3(4H)-one derivative 3	DMA430E	N. A.	N. A.	Patented	[2]
Azetidinyl-piperazine derivative 1	DMMWK3E	N. A.	N. A.	Patented	[2]
Azetidinyl-piperazine derivative 2	DM0C48S	N. A.	N. A.	Patented	[2]
Azetidinyl-piperazine derivative 3	DM3WHL2	N. A.	N. A.	Patented	[2]
Azetidinyl-piperidine derivative 1	DM0IJYQ	N. A.	N. A.	Patented	[2]
Azetidinyl-piperidine derivative 2	DMNQLJU	N. A.	N. A.	Patented	[2]
Azetidinyl-piperidine derivative 3	DM2UDV8	N. A.	N. A.	Patented	[2]
Carbamate derivative 10	DMP98CL	N. A.	N. A.	Patented	[2]
Carbamate derivative 11	DM3CF91	N. A.	N. A.	Patented	[2]
Carbamate derivative 12	DMMH27J	N. A.	N. A.	Patented	[2]
Carbamate derivative 13	DMLH45M	N. A.	N. A.	Patented	[2]
Carbamate derivative 14	DMZS0HT	N. A.	N. A.	Patented	[2]
Carbamate derivative 15	DMOKC41	N. A.	N. A.	Patented	[2]
Carbamate derivative 16	DMPLZSE	N. A.	N. A.	Patented	[2]
Carbamate derivative 17	DMYSRPT	N. A.	N. A.	Patented	[2]
Carbamate derivative 9	DMW4B1U	N. A.	N. A.	Patented	[2]
Carbamide derivative 24	DMD6Y73	N. A.	N. A.	Patented	[2]
Carbamide derivative 25	DM8ONCL	N. A.	N. A.	Patented	[2]
Carbamide derivative 26	DMDU9XF	N. A.	N. A.	Patented	[2]
Piperazine carbamic compound 1	DMZSYU4	N. A.	N. A.	Patented	[2]
Piperazine carbamic compound 2	DMMQ0ZO	N. A.	N. A.	Patented	[2]
Piperazine carbamic compound 3	DM8IU1G	N. A.	N. A.	Patented	[2]
Piperazine carbamic compound 4	DMKZUO4	N. A.	N. A.	Patented	[2]
Piperazine carbamic compound 5	DMXH65Z	N. A.	N. A.	Patented	[2]
PMID29053063-Compound-11c	DMLMHR5	N. A.	N. A.	Patented	[2]
PMID29053063-Compound-11d	DMDRK68	N. A.	N. A.	Patented	[2]
PMID29053063-Compound-14	DMBR72X	N. A.	N. A.	Patented	[2]
PMID29053063-Compound-15	DM07U5R	N. A.	N. A.	Patented	[2]
PMID29053063-Compound-17	DMRHPN0	N. A.	N. A.	Patented	[2]
PMID29053063-Compound-4	DM8RAK0	N. A.	N. A.	Patented	[2]
PMID29053063-Compound-5	DM2P05S	N. A.	N. A.	Patented	[2]
PMID29053063-Compound-7a	DMTOHNQ	N. A.	N. A.	Patented	[2]
PMID29053063-Compound-7b	DMDJ6O8	N. A.	N. A.	Patented	[2]
PMID29053063-Compound-7c	DMNZO7V	N. A.	N. A.	Patented	[2]
PMID29053063-Compound-7d	DMUNXAR	N. A.	N. A.	Patented	[2]
PMID29053063-Compound-7e	DM6XYFB	N. A.	N. A.	Patented	[2]
PMID29053063-Compound-7f	DMIQ263	N. A.	N. A.	Patented	[2]
Pyrazole derivative 80	DMQ3TGM	N. A.	N. A.	Patented	[2]
Pyrazole derivative 81	DMWT437	N. A.	N. A.	Patented	[2]
Pyrazole derivative 82	DMETCI3	N. A.	N. A.	Patented	[2]
Pyrazole derivative 83	DMMGLOA	N. A.	N. A.	Patented	[2]
Pyrazole derivative 84	DME8Q0F	N. A.	N. A.	Patented	[2]
Pyrazole derivative 85	DMNBCKI	N. A.	N. A.	Patented	[2]

1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
JZL184	DMWA8B0	Discovery agent	N.A.	Investigative	[3]

References

• [1] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [2] A patent review of Monoacylglycerol Lipase (MAGL) inhibitors (2013-2017).Expert Opin Ther Pat. 2017 Dec;27(12):1341-1351.
• [3] Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects. Nat Chem Biol. 2009 Jan;5(1):37-44.