Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTZJD1B)

• DTT Name: Acetylcholine release (Ach rele) DTT Info
• Gene Name: Ach rele

Molecule-Related Drug & Molecule List

2 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Abobotulinum toxin A	DMZT2P0	Cervical cancer	2C77.0	Approved	[1]
Incobotulinum toxin A	DMKE6YT	Cervical cancer	2C77.0	Approved	[2]

2 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
HOE-065	DMNC1A3	Cognitive impairment	6D71	Discontinued in Phase 1	[3]
KW-6055	DM76O23	Inflammation	1A00-CA43.1	Discontinued in Phase 1	[4]

References

• [1] Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92.
• [2] Mullard A: 2010 FDA drug approvals. Nat Rev Drug Discov. 2011 Feb;10(2):82-5.
• [3] Effects of the novel compound, Hoe 065, upon impaired learning and memory in rodents. Eur J Pharmacol. 1989 Nov 14;171(1):79-85.
• [4] Effects of KW-6055, a novel benzylpyridine derivative, on central cholinergic systems. Nihon Yakurigaku Zasshi. 1992 Jun;99(6):435-43.