Details of Disease

General Information of Disease (ID: DIS0D4QQ)

Disease Name Pancreatic cancer, susceptibility to, 4
Synonyms
PNCA4; susceptibility to pancreatic cancer 4; familial pancreatic carcinoma caused by mutation in BRCA1; pancreatic cancer, susceptibility to, type 4; pancreatic cancer, susceptibility to, 4; BRCA1 familial pancreatic carcinoma
Definition Any familial pancreatic carcinoma in which the cause of the disease is a mutation in the BRCA1 gene.
Disease Hierarchy
DISGXLG5: Hereditary neoplastic syndrome
DIS98MYE: Inherited disease susceptibility
DIS0D4QQ: Pancreatic cancer, susceptibility to, 4
Disease Identifiers
MONDO ID
MONDO_0013685
UMLS CUI
C3280442
OMIM ID
614320
MedGen ID
482072

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
BRCA1 OT5BN6VH Moderate Autosomal dominant [1]
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References

1 Current Approaches to Pancreatic Cancer Screening. Am J Pathol. 2019 Jan;189(1):22-35. doi: 10.1016/j.ajpath.2018.09.013.