Details of Disease
General Information of Disease (ID: DIS225UQ)
| Disease Name | T-B- severe combined immunodeficiency | |||||
|---|---|---|---|---|---|---|
| Synonyms | T-B- SCID | |||||
| Definition | 
                                         
                        T-B- severe combined immunodeficiency (SCID) is a group of rare monogenic primary immunodeficiency disorders characterized by a lack of functional peripheral T and B lymphocytes, resulting in recurrent early-onset severe respiratory viral, bacterial or fungal infections, diarrhea and failure to thrive. Hypersensitivity to ionizing radiation is a characteristic feature of some of its sub-types.
                        
                     
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