Details of Disease

General Information of Disease (ID: DIS2724M)

Disease Name	Enthesopathy
Synonyms	enthesis disease or disorder; enthesis disease; disorder of enthesis; disease or disorder of enthesis; disease of enthesis
Disease Class	FB53-FB55: Enthesopathy
Definition	A disorder involving the attachment of a tendon or ligament to a bone
Disease Hierarchy	DISWD40R: Disease DISPPN0O: Musculoskeletal disorder DISKXBS3: Connective tissue disorder DIS2724M: Enthesopathy
ICD Code	ICD-11 ICD-11: FB53-FB55 ICD-10 ICD-10: M77.9 ICD-9 ICD-9: 726 Expand ICD-11 'FB55 Expand ICD-10 'M77.9 Expand ICD-9 726
Disease Identifiers	MONDO ID MONDO_0002183 MESH ID D000070676 UMLS CUI C0242490 MedGen ID 66909 SNOMED CT ID 23680005

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 1 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Hyaluronate sodium	DMX8M26	Approved	Small molecular drug	[1]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
ACAD8	OT3JI5GB	Strong	Genetic Variation	[2]
CD5L	OTPY4WQR	Strong	Biomarker	[3]
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References

1	Clinical pipeline report, company report or official report of Genentech.
2	Emergence of severe spondyloarthropathy-related entheseal pathology following successful vedolizumab therapy for inflammatory bowel disease.Rheumatology (Oxford). 2019 Jun 1;58(6):963-968. doi: 10.1093/rheumatology/key267.
3	Foot functions in ankylosing spondylitis.Clin Rheumatol. 2019 Apr;38(4):1083-1088. doi: 10.1007/s10067-018-4386-6. Epub 2018 Dec 3.