Details of Disease

General Information of Disease (ID: DIS2XZ0U)

• Disease Name: Appendiceal neoplasm
• Synonyms: vermiform appendix tumour; vermiform appendix tumor; vermiform appendix neoplasm (disease); vermiform appendix neoplasm; tumour of vermiform appendix; tumour of the appendix; tumour of appendix; tumor of vermiform appendix; tumor of the appendix; tumor of appendix; neoplasm of vermiform appendix; neoplasm of the appendix; neoplasm of appendix; appendix tumour; appendix tumor; appendix neoplasm
• Definition: A benign or malignant neoplasm involving the appendix.
• Disease Hierarchy:
  DISTBY9Z: Tumour
  DISV4OKA: Cecal neoplasm
  DIS5PNPO: Disorder of appendix
  DIS2XZ0U: Appendiceal neoplasm
• Disease Identifiers:
  MONDO ID: MONDO_0001236
  MESH ID: D001063
  UMLS CUI: C0003614
  MedGen ID: 1629
  SNOMED CT ID: 126846004

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 2 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Irinotecan	DMP6SC2	Approved	Small molecular drug	[1]
Oxaliplatin	DMQNWRD	Approved	Small molecular drug	[2]

Molecular Interaction Atlas (MIA) of This Disease

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
SATB2	OT2W80XC	Strong	Altered Expression	[3]

References

• [1] Irinotecan FDA Label
• [2] Oxaliplatin FDA Label
• [3] SATB2 protein expression by immunohistochemistry is a sensitive and specific marker of appendiceal and rectosigmoid well differentiated neuroendocrine tumours.Histopathology. 2020 Mar;76(4):550-559. doi: 10.1111/his.14012. Epub 2020 Jan 24.