Details of Disease | DrugMAP

General Information of Disease (ID: DIS4L7UT)

Disease Name	Spermatogenic failure, X-linked, 2
Synonyms	Male infertility from defect in meiosis; SPGFX2; azoospermia caused by mutation in TEX11; spermatogenic failure, X-linked, type 2; spermatogenic failure, X-linked, 2, X-linked recessive; spermatogenic failure, X-linked, 2; TEX11 azoospermia
Definition	Any azoospermia in which the cause of the disease is a mutation in the TEX11 gene.
Disease Hierarchy	DIS3D1AI: Spermatogenic failure DIS4L7UT: Spermatogenic failure, X-linked, 2
Disease Identifiers	MONDO ID MONDO_0010647 UMLS CUI C1839841 OMIM ID 309120 MedGen ID 374322

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
TEX11	OTJDBGSS	Strong	X-linked	[1]
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References

1	Meiotic failure in male mice lacking an X-linked factor. Genes Dev. 2008 Mar 1;22(5):682-91. doi: 10.1101/gad.1613608.