Details of Disease

General Information of Disease (ID: DIS4X4VM)

• Disease Name: Inflammatory bowel disease 1
• Synonyms: regional enteritis; ulcerative colitis; Crohn disease; ulcerative colitis, paediatric; Crohn disease-associated Growth failure, susceptibility to; inflammatory bowel disease (Crohn disease) 1; pediatric ulcerative colitis; ulcerative colitis, pediatric; paediatric ulcerative colitis; inflammatory bowel disease 1, Crohn disease; NOD2 inflammatory bowel disease; inflammatory bowel disease 1; inflammatory bowel disease type 1; crohn disease-associated growth failure; inflammatory bowel disease caused by mutation in NOD2; IBD1
• Definition: Any inflammatory bowel disease in which the cause of the disease is a mutation in the NOD2 gene.
• Disease Hierarchy:
  DISGN23E: Inflammatory bowel disease
  DIS4X4VM: Inflammatory bowel disease 1

Molecular Interaction Atlas (MIA) of This Disease

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
NOD2	TTYPUHA	Limited	Unknown	[1]

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
NOD2	OTPGYWKC	Limited	Unknown	[1]

References

• [1] CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease. Am J Hum Genet. 2002 Apr;70(4):845-57. doi: 10.1086/339432. Epub 2002 Mar 1.