Details of Disease | DrugMAP

General Information of Disease (ID: DIS5FPQO)

Disease Name	Maturity-onset diabetes of the young type 10
Synonyms	maturity-onset diabetes of the young, type 10; maturity-onset diabetes of the young (disease) caused by mutation in INS; MODY10; INS maturity-onset diabetes of the young (disease)
Definition	Any maturity-onset diabetes of the young in which the cause of the disease is a mutation in the INS gene.
Disease Hierarchy	DISG75M5: Maturity-onset diabetes of the young DIS5FPQO: Maturity-onset diabetes of the young type 10
Disease Identifiers	MONDO ID MONDO_0013240 UMLS CUI C3150617 OMIM ID 613370 MedGen ID 461967 SNOMED CT ID 609577006

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 2 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
INS	TTZOPHG	Strong	Autosomal dominant	[1]
INS	TTZOPHG	Strong	Genetic Variation	[2]
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This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
INS	OTZ85PDU	Strong	Autosomal dominant	[1]
INS-IGF2	OTZR74BO	Strong	Genetic Variation	[2]
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References

1	The Gene Curation Coalition: A global effort to harmonize gene-disease evidence resources. Genet Med. 2022 Aug;24(8):1732-1742. doi: 10.1016/j.gim.2022.04.017. Epub 2022 May 4.
2	INS-gene mutations: from genetics and beta cell biology to clinical disease.Mol Aspects Med. 2015 Apr;42:3-18. doi: 10.1016/j.mam.2014.12.001. Epub 2014 Dec 24.