Details of Disease | DrugMAP

General Information of Disease (ID: DIS5QMRP)

Disease Name	Breast-ovarian cancer, familial, susceptibility to, 4
Synonyms	BROVCA4; susceptibility to familial breast-ovarian cancer 4; RAD51D hereditary breast ovarian cancer syndrome; breast-ovarian cancer, familial, susceptibility to, 4; hereditary breast ovarian cancer syndrome caused by mutation in RAD51D; breast-ovarian cancer, familial, susceptibility to, type 4
Definition	Any hereditary breast ovarian cancer syndrome in which the cause of the disease is a mutation in the RAD51D gene.
Disease Hierarchy	DISHJXS0: Breast-ovarian cancer, familial, susceptibility to DIS98MYE: Inherited disease susceptibility DIS5QMRP: Breast-ovarian cancer, familial, susceptibility to, 4
Disease Identifiers	MONDO ID MONDO_0013669 UMLS CUI C3280345 OMIM ID 614291 MedGen ID 481975

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
RAD51D	OTKOU5XN	Strong	Autosomal dominant	[1]
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References

1	The Gene Curation Coalition: A global effort to harmonize gene-disease evidence resources. Genet Med. 2022 Aug;24(8):1732-1742. doi: 10.1016/j.gim.2022.04.017. Epub 2022 May 4.