Details of Disease

General Information of Disease (ID: DIS699VO)

Disease Name Phagocyte bactericidal dysfunction
Synonyms phagocytic dysfunction
Definition Disorders in which phagocytic cells cannot kill ingested bacteria; characterized by frequent recurring infection with formulation of granulomas.
Disease Hierarchy
DISA03DD: Phagocytic cell dysfunction
DIS17G9I: Leukocyte disorder
DISNGCMN: Inborn error of immunity
DIS699VO: Phagocyte bactericidal dysfunction
Disease Identifiers
MONDO ID
MONDO_0005910
MESH ID
D010585
UMLS CUI
C0031306
MedGen ID
14713

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
G6PD TTKN8W0 Limited Biomarker [1]
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References

1 Neutrophil dysfunction, chronic granulomatous disease, and non-spherocytic haemolytic anaemia caused by complete deficiency of glucose-6-phosphate dehydrogenase.Lancet. 1973 Sep 8;2(7828):530-4. doi: 10.1016/s0140-6736(73)92350-7.