Details of Disease

General Information of Disease (ID: DIS7DKX0)

Disease Name Tremor, hereditary essential, 5
Synonyms
tremor, hereditary essential, type 5; essential tremor, hereditary, 5; ETM5; essential tremor caused by mutation in TENM4; tremor, hereditary essential, 5; TENM4 essential tremor; tremor, hereditary essential, 5; ETM5
Definition Any essential tremor in which the cause of the disease is a mutation in the TENM4 gene.
Disease Hierarchy
DIS7GBKQ: Essential tremor
DIS7DKX0: Tremor, hereditary essential, 5
Disease Identifiers
MONDO ID
MONDO_0014756
UMLS CUI
C4225223
OMIM ID
616736
MedGen ID
897748

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
TENM4 OT91K3FC Strong Autosomal dominant [1]
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References

1 Teneurin-4 is a novel regulator of oligodendrocyte differentiation and myelination of small-diameter axons in the CNS. J Neurosci. 2012 Aug 22;32(34):11586-99. doi: 10.1523/JNEUROSCI.2045-11.2012.