Details of Disease

General Information of Disease (ID: DIS7PRLV)

• Disease Name: Primary mediastinal B-cell lymphoma
• Disease Class: 2A81: Diffuse large B-cell lymphoma
• Disease Hierarchy:
  DIS01GPL: Grass pollen hypersensitivity
  DIS7PRLV: Primary mediastinal B-cell lymphoma
• ICD Code:
  ICD-11: ICD-11: 2A81
  ICD-10: ICD-10: C83.3

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 2 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Axicabtagene ciloleucel	DMYHN59	Approved	CAR T Cell Therapy	[1]
Pembrolizumab	DMFQEA6	Approved	Monoclonal antibody	[1]

This Disease is Treated as An Indication in 2 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Anti-CD19-CAR PBL	DM1WB8H	Phase 1/2	CAR T Cell Therapy	[2]
JCAR017	DMJV2IF	Phase 1/2	CAR T Cell Therapy	[3]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [2] ClinicalTrials.gov (NCT00924326) CAR T Cell Receptor Immunotherapy for Patients With B-cell Lymphoma
• [3] ClinicalTrials.gov (NCT02631044) Study Evaluating the Safety and Pharmacokinetics of JCAR017 in B-cell Non-Hodgkin Lymphoma (TRANSCEND-NHL-001)