Details of Disease

Disease Name

Pneumonia caused by gram negative bacteria

gram negative pneumonia; gramme negative pneumonia; pneumonia due to gram-negative bacteria; pneumonia caused by gram-negative bacteria; pneumonia due to gram negative bacteria; pneumonia caused by gram negative bacteria; pneumonia due to gramme negative bacteria

Disease Hierarchy

DIS8MM3L: Gram-negative bacterial infection

DISPW7PH: Bacterial pneumonia

DISA4DV0: Pneumonia caused by gram negative bacteria

Disease Identifiers

MONDO ID

MONDO_0041850

UMLS CUI

C0854248

MedGen ID

678525

SNOMED CT ID

430395005

General Information of Disease (ID: DISA4DV0)

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 1 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Amikacin	DM5PDRB	Approved	Small molecular drug	[1]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
IL36G	TT8SLDN	Disputed	Genetic Variation	[2]
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This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
NBEAL2	OTMCAXWR	Strong	Biomarker	[3]
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References

1	Amikacin FDA Label
2	IL-36 is a crucial proximal component of protective type-1-mediated lung mucosal immunity in Gram-positive and -negative bacterial pneumonia.Mucosal Immunol. 2017 Sep;10(5):1320-1334. doi: 10.1038/mi.2016.130. Epub 2017 Feb 8.
3	Nbeal2 Deficiency Increases Organ Damage but Does Not Affect Host Defense During Gram-Negative Pneumonia-Derived Sepsis.Arterioscler Thromb Vasc Biol. 2018 Aug;38(8):1772-1784. doi: 10.1161/ATVBAHA.118.311332.