Details of Disease | DrugMAP

General Information of Disease (ID: DISBIR6Z)

Disease Name	Diabetes mellitus, transient neonatal, 2
Synonyms	Tndm2; transient neonatal diabetes mellitus (disease) caused by mutation in ABCC8; diabetes mellitus, transient neonatal, type 2; diabetes mellitus, transient neonatal 2; diabetes mellitus, transient neonatal, 2; ABCC8 transient neonatal diabetes mellitus (disease)
Definition	Any transient neonatal diabetes mellitus in which the cause of the disease is a mutation in the ABCC8 gene.
Disease Hierarchy	DIST826V: Transient neonatal diabetes mellitus DISBIR6Z: Diabetes mellitus, transient neonatal, 2
Disease Identifiers	MONDO ID MONDO_0012480 MESH ID C563672 UMLS CUI C1835887 OMIM ID 610374 MedGen ID 372150 SNOMED CT ID 609580007

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
ABCC8	TTP835K	Definitive	Genetic Variation	[1]
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This Disease Is Related to 1 DTP Molecule(s)

Gene Name	DTP ID	Evidence Level	Mode of Inheritance	REF
ABCC8	DTI58LU	Strong	Unknown	[2]
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This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
ABCC8	OTCWQ54I	Strong	Unknown	[2]
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References

1	Activating mutations in the ABCC8 gene in neonatal diabetes mellitus. N Engl J Med. 2006 Aug 3;355(5):456-66. doi: 10.1056/NEJMoa055068.
2	The Gene Curation Coalition: A global effort to harmonize gene-disease evidence resources. Genet Med. 2022 Aug;24(8):1732-1742. doi: 10.1016/j.gim.2022.04.017. Epub 2022 May 4.