Details of Disease | DrugMAP

General Information of Disease (ID: DISBXWAX)

Disease Name	Tooth disorder
Synonyms	calcareous tooth disease or disorder; calcareous tooth disease; disease of calcareous tooth; dental disorder; disorder of calcareous tooth; disease or disorder of calcareous tooth; tooth disorder
Definition	A disease involving the calcareous tooth.
Disease Hierarchy	DISX82BI: Mouth disorder DISWD40R: Disease DIS5PU87: Skeletal system disorder DISBXWAX: Tooth disorder
Disease Identifiers	MONDO ID MONDO_0006999 MESH ID D014076 UMLS CUI C0040435 MedGen ID 11852 SNOMED CT ID 234947003

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
RHOA	TTP2U16	Strong	Biomarker	[1]
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This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
FGD4	OTYXJQCW	Strong	Genetic Variation	[2]
GDAP1	OTQE1O25	Strong	Genetic Variation	[3]
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References

1	Postzygotic inactivating mutations of RHOA cause a mosaic neuroectodermal syndrome.Nat Genet. 2019 Oct;51(10):1438-1441. doi: 10.1038/s41588-019-0498-4. Epub 2019 Sep 30.
2	A novel Frabin (FGD4) nonsense mutation p.R275X associated with phenotypic variability in CMT4H.Neurology. 2009 Feb 17;72(7):617-20. doi: 10.1212/01.wnl.0000342463.35089.cc.
3	Vocal cord and diaphragm paralysis, as clinical features of a French family with autosomal recessive Charcot-Marie-Tooth disease, associated with a new mutation in the GDAP1 gene.Neuromuscul Disord. 2004 Apr;14(4):261-4. doi: 10.1016/j.nmd.2004.01.003.