Details of Disease

General Information of Disease (ID: DISCUUIU)

Disease Name Splenic disorder
Synonyms splenic disorder; splenic disease; spleen disorder; spleen disease or disorder; spleen disease; disorder of spleen; disease or disorder of spleen; disease of spleen; Dyssplenism
Definition A disease involving the spleen.
Disease Hierarchy
DISWD40R: Disease
DIS9XD9A: Hematologic disease
DIS57XO9: Lymphatic disease
DISCUUIU: Splenic disorder
Disease Identifiers
MONDO ID
MONDO_0002332
MESH ID
D013158
UMLS CUI
C0037997
MedGen ID
21291
SNOMED CT ID
51244008

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 2 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
AHR TT037IE Strong Biomarker [1]
CYP1A2 TTS1DTU Strong Biomarker [1]
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This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
TLX1 OTVN0MNW Strong Biomarker [2]
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References

1 In utero and lactational exposure to a complex mixture of polychlorinated biphenyls: toxicity in pups dependent on the Cyp1a2 and Ahr genotypes.Toxicol Sci. 2011 Jan;119(1):189-208. doi: 10.1093/toxsci/kfq314. Epub 2010 Oct 20.
2 Hox11 controls the genesis of the spleen.Nature. 1994 Apr 21;368(6473):747-9. doi: 10.1038/368747a0.