Details of Disease

General Information of Disease (ID: DISD3GU2)

Disease Name Diarrhea-predominant irritable bowel syndrome
Disease Class DD91: Irritable bowel syndrome
Disease Hierarchy
DIS01GPL: Grass pollen hypersensitivity
DISD3GU2: Diarrhea-predominant irritable bowel syndrome
ICD Code
ICD-11
ICD-11: DD91.01
ICD-10
ICD-10: K58.0
ICD-9
ICD-9: 564.1
Expand ICD-11
'DD91.01
Expand ICD-10
'K58.0
Expand ICD-9
564.1

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 5 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Alosetron DML2A03 Approved Small molecular drug [1]
Eluxadoline DMYZ0P1 Approved Small molecular drug [2]
Ramosetron DMH7GN8 Approved Small molecular drug [3]
Ranolazine DM0C9IL Approved Small molecular drug [4]
Rifaximin DMW1TV2 Approved Small molecular drug [5]
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This Disease is Treated as An Indication in 1 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Asimadoline DMND3AB Phase 3 Small molecular drug [6]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1 Alosetron FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7691).
3 Current and emerging pharmacological approaches for treating diarrhea-predominant irritable bowel syndrome. Expert Opin Pharmacother. 2020 Jan;21(1):63-71.
4 Ranolazine FDA Label
5 Rifaximin FDA Label
6 Emerging drugs for irritable bowel syndrome. Expert Opin Emerg Drugs. 2006 May;11(2):293-313.