Details of Disease | DrugMAP

General Information of Disease (ID: DISDMSC5)

Disease Name	Erythrocyte disorder
Synonyms	red blood cell disorder; erythrocyte disease or disorder; erythrocyte disease; disease or disorder of erythrocyte; red blood cell disease; disorder of erythrocyte; disease of erythrocyte
Definition	A disease or disorder that involves the erythrocyte.
Disease Hierarchy	DIS9XD9A: Hematologic disease DISWD40R: Disease DISDMSC5: Erythrocyte disorder
Disease Identifiers	MONDO ID MONDO_0044347 UMLS CUI C0221016 MedGen ID 526127 SNOMED CT ID 38292009

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
PKLR	TT31N4S	Strong	Biomarker	[1]
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This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
KLF1	OT1FK08U	Limited	Biomarker	[2]
HBG1	OTVL4NSU	Strong	Biomarker	[3]
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References

1	Path to facilitate the prediction of functional amino acid substitutions in red blood cell disorders--a computational approach.PLoS One. 2011;6(9):e24607. doi: 10.1371/journal.pone.0024607. Epub 2011 Sep 13.
2	Differential role of Kruppel like factor 1 (KLF1) gene in red blood cell disorders.Genomics. 2019 Dec;111(6):1771-1776. doi: 10.1016/j.ygeno.2018.11.032. Epub 2018 Dec 5.
3	Understanding globin regulation in beta-thalassemia: it's as simple as alpha, beta, gamma, delta.J Clin Invest. 2005 Jun;115(6):1470-3. doi: 10.1172/JCI25398.