Details of Disease | DrugMAP

General Information of Disease (ID: DISE7ZR0)

Disease Name	Nail disorder
Synonyms	nail disease or disorder; nail disease; disorder of nail; disease or disorder of nail; disease of nail
Definition	A disease involving the nail.
Disease Hierarchy	DISWD40R: Disease DISTXWNT: Integumentary system disorder DISE7ZR0: Nail disorder
Disease Identifiers	MONDO ID MONDO_0002884 MESH ID D009260 UMLS CUI C0027339 MedGen ID 10171 SNOMED CT ID 17790008

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
LAMA3	OTFME7HT	Strong	Biomarker	[1]
TINF2	OT861N2N	Definitive	Biomarker	[2]
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References

1	An unusual N-terminal deletion of the laminin alpha3a isoform leads to the chronic granulation tissue disorder laryngo-onycho-cutaneous syndrome. Hum Mol Genet. 2003 Sep 15;12(18):2395-409. doi: 10.1093/hmg/ddg234. Epub 2003 Jul 15.
2	TINF2, a component of the shelterin telomere protection complex, is mutated in dyskeratosis congenita. Am J Hum Genet. 2008 Feb;82(2):501-9. doi: 10.1016/j.ajhg.2007.10.004. Epub 2008 Jan 31.