Details of Disease | DrugMAP

General Information of Disease (ID: DISE81BQ)

Disease Name	Mismatch repair cancer syndrome 2
Synonyms	MMRCS2; mismatch repair cancer syndrome 2
Disease Hierarchy	DISIXHJ2: Mismatch repair cancer syndrome DISE81BQ: Mismatch repair cancer syndrome 2
Disease Identifiers	MONDO ID MONDO_0030840 MESH ID C536928 UMLS CUI C5436806 OMIM ID 619096 MedGen ID 1750327

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
MSH2	TTCAWRT	Strong	Autosomal recessive	[1]
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This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
MSH2	OT10H1AB	Strong	Autosomal recessive	[1]
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References

1	Spectrum and frequencies of mutations in MSH2 and MLH1 identified in 1,721 German families suspected of hereditary nonpolyposis colorectal cancer. Int J Cancer. 2005 Sep 20;116(5):692-702. doi: 10.1002/ijc.20863.