Details of Disease

General Information of Disease (ID: DISEHLU2)

• Disease Name: Vaginal disease
• Synonyms: vaginal disorder; vaginal disease; vagina disease or disorder; vagina disease; disorder of vagina; disease or disorder of vagina; disease of vagina
• Disease Class: GA1Y: Female genital tract noninflammatory disorder
• Definition: A non-neoplastic or neoplastic disorder that affects the vagina. Representative examples include vaginal infection, vaginal polyp, and vaginal squamous cell carcinoma.
• Disease Hierarchy:
  DISWD40R: Disease
  DISXEPZF: Gynecological disease
  DISEHLU2: Vaginal disease
• ICD Code:
  ICD-11: ICD-11: GA1Y
  Expand ICD-11: 'GA1Y
• Disease Identifiers:
  MONDO ID: MONDO_0001433
  MESH ID: D014623
  UMLS CUI: C0042251
  MedGen ID: 12042
  SNOMED CT ID: 25658005

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 2 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Synthetic conjugated estrogen	DMRUEKC	Phase 3	NA	[1]
TOL-463	DM8VV80	Phase 2	NA	[2]

Molecular Interaction Atlas (MIA) of This Disease

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
ACKR1	TTKY2NS	Limited	Biomarker	[3]

References

• [1] ClinicalTrials.gov (NCT00361569) A Clinical Trial to Evaluate the Safety and Efficacy of DR-2041(Synthetic Conjugated Estrogens, A) for Treatment of Vulvovaginal Atrophy. U.S. National Institutes of Health.
• [2] ClinicalTrials.gov (NCT01812889) Evaluation of Intravaginal Gel and Ovule Formulations of TOL-463. U.S. National Institutes of Health.
• [3] A Dual-Modality Herpes Simplex Virus 2 Vaccine for Preventing Genital Herpes by Using Glycoprotein C and D Subunit Antigens To Induce Potent Antibody Responses and Adenovirus Vectors Containing Capsid and Tegument Proteins as T Cell Immunogens.J Virol. 2015 Aug;89(16):8497-509. doi: 10.1128/JVI.01089-15. Epub 2015 Jun 3.