Details of Disease

Disease Name

Anemia of prematurity

Definition

A blood disorder characterized by low hemoglobin levels in premature neonates that usually spontaneously resolves within 3-6 months post birth. A combination of factors including the transition from the liver to the bone marrow for erythropoiesis in a neonate, blood loss experienced during delivery, the shortened life span of fetal blood cells, and an acclimation to a relatively hyperoxic environment outside the womb can predispose a neonate to this condition.

Disease Hierarchy

DISPFC78: Neonatal anemia

DISFVUT9: Anemia of prematurity

Disease Identifiers

MONDO ID

MONDO_0001239

UMLS CUI

C0158996

MedGen ID

472907

SNOMED CT ID

47100003

General Information of Disease (ID: DISFVUT9)

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 2 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Iron	DMAP8MV	Approved	Small molecular drug	[1]
Sodium ferric gluconate complex	DMF699X	Approved	Small molecular drug	[2]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DME Molecule(s)

Gene Name	DME ID	Evidence Level	Mode of Inheritance	REF
SMOX	DEOH5V3	Strong	Altered Expression	[3]
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References

1	Iron FDA Label
2	A standard database for drug repositioning. Sci Data. 2017 Mar 14;4:170029.
3	Gene expression in Pseudomonas aeruginosa exposed to hydroxyl-radicals.Chemosphere. 2018 May;199:243-250. doi: 10.1016/j.chemosphere.2018.02.012. Epub 2018 Feb 3.