Details of Disease

Disease Name

Psychosexual disorder

non-organic sexual dysfunction

Disease Hierarchy

DISXXLFD: Male sexual disorder

DIS3J5R8: Mental disorder

DISGQK8E: Psychosexual disorder

Disease Identifiers

MONDO ID

MONDO_0000947

MESH ID

D020018

UMLS CUI

C0033953

MedGen ID

18747

SNOMED CT ID

56627002

General Information of Disease (ID: DISGQK8E)

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 2 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Flibanserin	DM70DTN	Approved	Small molecular drug	[1]
Norepinephrine	DMOUC09	Approved	Small molecular drug	[2]
------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 6 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
GRIA1	TTVPQTF	Strong	Biomarker	[3]
GRIA3	TT82EZV	Strong	Biomarker	[3]
GRIK2	TT0K5RG	Strong	Biomarker	[3]
PRL	TTJ2TSA	Strong	Biomarker	[4]
CYP17A1	TTRA5BZ	Definitive	Biomarker	[5]
CYP2D6	TTVG215	Definitive	Biomarker	[6]
------------------------------------------------------------------------------------


⏷ Show the Full List of 6 DTT(s)

References

1	Flibanserin FDA Label
2	Norepinephrine FDA Label
3	Genetic and clinical predictors of sexual dysfunction in citalopram-treated depressed patients. Neuropsychopharmacology. 2009 Jun;34(7):1819-28. doi: 10.1038/npp.2009.4. Epub 2009 Mar 18.
4	Testosterone replacement-induced hyperprolactinaemia: case report and review of the literature.Ann Clin Biochem. 2005 Mar;42(Pt 2):153-9. doi: 10.1258/0004563053492784.
5	Haploinsufficiency of cytochrome P450 17alpha-hydroxylase/17,20 lyase (CYP17) causes infertility in male mice.Mol Endocrinol. 2005 Sep;19(9):2380-9. doi: 10.1210/me.2004-0418. Epub 2005 May 12.
6	Links among paroxetine-induced sexual dysfunctions, gender, and CYP2D6 activity.J Sex Marital Ther. 2007 Jul-Sep;33(4):343-55. doi: 10.1080/00926230701385589.