Details of Disease

General Information of Disease (ID: DISHV9EH)

Disease Name Epidemic louse-borne typhus
Synonyms typhus; epidemic typhus fever; epidemic typhus; epidemic louse-borne typhus; sylvatic typhus
Definition
A gram-negative bacterial infection caused by Rickettsia prowazekii. It is spread by lice infected with the bacteria. Signs and symptoms include sudden headache, generalized muscle pain, malaise, and macular skin lesions. The infection may affect the central nervous system causing encephalitis.
Disease Hierarchy
DISJ5JX1: Typhus
DISHV9EH: Epidemic louse-borne typhus
Disease Identifiers
MONDO ID
MONDO_0019362
MESH ID
D014438
UMLS CUI
C0041473
MedGen ID
21744
Orphanet ID
83314
SNOMED CT ID
39111003

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 2 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Doxycycline DM7ICNU Approved Small molecular drug [1]
Fusidic Acid DMWVCF3 Approved Small molecular drug [2]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1 Doxycycline FDA Label
2 A standard database for drug repositioning. Sci Data. 2017 Mar 14;4:170029.