Details of Disease

General Information of Disease (ID: DISI893M)

• Disease Name: Severe pre-eclampsia
• Synonyms: severe preeclampsia; severe pre-eclampsia, with delivery; postpartum severe pre-eclampsia; antepartum severe pre-eclampsia; Preeclampsia with severe features
• Definition: Preeclampsia with a systolic blood pressure of 160 mmHg or higher, or a diastolic blood pressure of 110 mmHg or higher on two occasions at least 4 hours apart while on bedrest. It is associated with thrombocytopenia (platelets less than 100,000 per microliter), impaired liver function (twice normal elevation of hepatic transaminases; severe, persistent right upper quadrant or epigastric pain), progressive renal insufficiency (serum creatinine greater than 1.1 mg/dL or doubling of baseline in the absence of other renal disease), pulmonary edema, or new-onset cerebral or visual disturbances.
• Disease Hierarchy:
  DISY7Q29: Pre-eclampsia
  DISI893M: Severe pre-eclampsia
• Disease Identifiers:
  MONDO ID: MONDO_0001641
  UMLS CUI: C0341950
  MedGen ID: 574734
  SNOMED CT ID: 46764007

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 1 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Magnesium Sulfate	DMVEK07	Approved	Small molecular drug	[1]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] Magnesium Sulfate FDA Label