Details of Disease | DrugMAP

General Information of Disease (ID: DISIENZM)

Disease Name	Neuroma
Definition	A tumor that grows from a nerve or is composed of nerve cells and nerve fibers.\|Note that this class represents a grouping of benign neoplasms plus non-neoplastic swellings and growth such as traumatic neuromas. In future it may be split
Disease Hierarchy	DISRUHOW: Peripheral nervous system disorder DISIENZM: Neuroma
Disease Identifiers	MONDO ID MONDO_0002173 MESH ID D009463 UMLS CUI C0027858 MedGen ID 14352 HPO ID HP:0030430 SNOMED CT ID 1163436007

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
ANK3	OTJ3IRBP	Strong	Biomarker	[1]
SEMA3F	OTQFMS8S	Strong	Biomarker	[2]
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References

1	Ankyrin G and voltage gated sodium channels colocalize in human neuroma--key proteins of membrane remodeling after axonal injury.Neurosci Lett. 2002 Apr 26;323(2):151-5. doi: 10.1016/s0304-3940(02)00021-6.
2	Human neuroma contains increased levels of semaphorin 3A, which surrounds nerve fibers and reduces neurite extension in vitro.J Neurosci. 2007 Dec 26;27(52):14260-4. doi: 10.1523/JNEUROSCI.4571-07.2007.