Details of Disease | DrugMAP

General Information of Disease (ID: DISJT0KF)

Disease Name	HTRA1-related autosomal dominant cerebral small vessel disease
Synonyms	HTRA1-related autosomal dominant cerebral angiopathy
Disease Hierarchy	DISAB237: Cerebrovascular disease DISJT0KF: HTRA1-related autosomal dominant cerebral small vessel disease
Disease Identifiers	MONDO ID MONDO_0018832 UMLS CUI C5568568 MedGen ID 1799991 Orphanet ID 482077 SNOMED CT ID 1186724002

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
HTRA1	TT8POQR	Supportive	Autosomal dominant	[1]
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This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
HTRA1	OTR8ACBF	Supportive	Autosomal dominant	[1]
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References

1	Heterozygous HTRA1 mutations are associated with autosomal dominant cerebral small vessel disease. Brain. 2015 Aug;138(Pt 8):2347-58. doi: 10.1093/brain/awv155. Epub 2015 Jun 10.