Details of Disease | DrugMAP

General Information of Disease (ID: DISL1TMA)

Disease Name	Atrial fibrillation, familial, 7
Synonyms	ATFB7; atrial fibrillation, familial, 7; atrial fibrillation, familial, type 7; familial atrial fibrillation caused by mutation in KCNA5; KCNA5 familial atrial fibrillation
Definition	Any familial atrial fibrillation in which the cause of the disease is a mutation in the KCNA5 gene.
Disease Hierarchy	DISL4AGF: Familial atrial fibrillation DISL1TMA: Atrial fibrillation, familial, 7
Disease Identifiers	MONDO ID MONDO_0012828 MESH ID C567389 UMLS CUI C2677106 OMIM ID 612240 MedGen ID 393658

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTP Molecule(s)

Gene Name	DTP ID	Evidence Level	Mode of Inheritance	REF
KCNA5	DTGDWVS	Strong	Autosomal dominant	[1]
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This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
KCNA5	OTHI2N71	Strong	Autosomal dominant	[1]
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References

1	Classification of Genes: Standardized Clinical Validity Assessment of Gene-Disease Associations Aids Diagnostic Exome Analysis and Reclassifications. Hum Mutat. 2017 May;38(5):600-608. doi: 10.1002/humu.23183. Epub 2017 Feb 13.