Details of Disease

General Information of Disease (ID: DISLE27J)

Disease Name Rhegmatogenous retinal detachment
Definition Retinal detachment secondary to retinal tear or break.
Disease Hierarchy
:
DISLE27J: Rhegmatogenous retinal detachment
Disease Identifiers
MONDO ID
MONDO_0005464
UMLS CUI
C0271055
MedGen ID
489829
HPO ID
HP:0012230
SNOMED CT ID
19620000

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 8 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ALDOA OTWRFTIB Strong Biomarker [1]
CAPN5 OTQ8QM7K Strong Biomarker [2]
CCL26 OT2B7HR9 Strong Biomarker [3]
FZD4 OTGLZIE0 Strong Biomarker [4]
MTFMT OT1OIVJL Strong Biomarker [5]
NDP OTGDJ4US Strong Biomarker [4]
RPE OT0XT3JU Strong Biomarker [6]
CERS2 OTRAHYYP Definitive Genetic Variation [7]
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⏷ Show the Full List of 8 DOT(s)

References

1 iTRAQ Quantitative Proteomic Analysis of Vitreous from Patients with Retinal Detachment.Int J Mol Sci. 2018 Apr 11;19(4):1157. doi: 10.3390/ijms19041157.
2 Proteomic insight into the pathogenesis of CAPN5-vitreoretinopathy.Sci Rep. 2019 May 20;9(1):7608. doi: 10.1038/s41598-019-44031-7.
3 Cytokine profiles of phakic and pseudophakic eyes with primary retinal detachment.Acta Ophthalmol. 2019 Jun;97(4):e580-e588. doi: 10.1111/aos.13998. Epub 2018 Dec 18.
4 CLINICAL FEATURES OF AFFECTED AND UNDETACHED FELLOW EYES IN PATIENTS WITH FEVR-ASSOCIATED RHEGMATOGENOUS RETINAL DETACHMENT.Retina. 2017 Mar;37(3):585-591. doi: 10.1097/IAE.0000000000001171.
5 Vascular changes after vitrectomy for rhegmatogenous retinal detachment: optical coherence tomography angiography study.Acta Ophthalmol. 2020 Aug;98(5):e563-e569. doi: 10.1111/aos.14315. Epub 2019 Nov 26.
6 Comparison between refractive outcomes between macula-on and macula-off retinal detachments after phaco-vitrectomy.Jpn J Ophthalmol. 2019 Jul;63(4):310-316. doi: 10.1007/s10384-019-00667-6. Epub 2019 Apr 20.
7 Genome-wide association study identifies genetic risk underlying primary rhegmatogenous retinal detachment.Hum Mol Genet. 2013 Aug 1;22(15):3174-85. doi: 10.1093/hmg/ddt169. Epub 2013 Apr 11.