Details of Disease

General Information of Disease (ID: DISLZYDI)

Disease Name	Pediculus capitis infestation
Synonyms	infections, Pediculus humanus capitis; pediculosis capitis; head louse infestation; Pediculus humanus capitis infection; Pediculus capitis infestation; Pediculus capitis [head louse]; Pediculus capitis
Disease Class	1G00: Pediculosis
Definition	A infectious disease involving Pediculus humanus capitis.
Disease Hierarchy	DISIC557: Lice infestation DISEM33Q: Infectious disease DISLZYDI: Pediculus capitis infestation
ICD Code	ICD-11 ICD-11: 1G00.0 ICD-10 ICD-10: B85.0 Expand ICD-11 '1G00.0 Expand ICD-10 'B85.0
Disease Identifiers	MONDO ID MONDO_0003471 UMLS CUI C0030757 MedGen ID 508022 SNOMED CT ID 81000006

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 5 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Lidocaine	DML4ZOT	Approved	Small molecular drug	[1]
Lindane	DMB8CNL	Approved	Small molecular drug	[2]
Malathion	DMXZ84M	Approved	Small molecular drug	[3]
Permethrin	DMZ0Q1G	Approved	Small molecular drug	[4]
Spinosad	DM0BQRS	Approved	Small molecular drug	[5]
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This Disease is Treated as An Indication in 2 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
BGC-20-0582	DMG13B9	Phase 2	NA	[6]
DeOvo	DMEUYU1	Phase 2	NA	[7]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
COX1	OTG3O9BN	Definitive	Biomarker	[8]
CYTB	OTAHB98A	Definitive	Genetic Variation	[9]
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References

1	Lidocaine FDA Label
2	Lindane FDA Label
3	FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 078743.
4	Permethrin FDA Label
5	Spinosad FDA Label
6	ClinicalTrials.gov (NCT00528021) A Study Evaluating the Safety and Efficacy of BGC20-0582 Lice Treatment Gel for Head Lice Infestation. U.S. National Institutes of Health.
7	Clinical pipeline report, company report or official report of Hatchtech.
8	Mitochondrial diversity and phylogeographic analysis of Pediculus humanus reveals a new Amazonian clade "F".Infect Genet Evol. 2019 Jun;70:1-8. doi: 10.1016/j.meegid.2019.02.006. Epub 2019 Feb 12.
9	Detection of bacterial pathogens in clade E head lice collected from Niger's refugees in Algeria.Parasit Vectors. 2018 Jun 15;11(1):348. doi: 10.1186/s13071-018-2930-5.