Details of Disease

General Information of Disease (ID: DISMK3AH)

Disease Name Discoid lupus erythematosus
Synonyms DLE
Disease Class EB50-EB5Z: Cutaneous lupus erythematosus
Definition
A chronic, autoimmune skin condition that manifests with a red, scaling rash, most often found on the face, ears, and scalp; these lesions often lead to permanent scarring and dyspigmentation. Patients may have lesions with or without other symptoms or antibodies suggestive of systemic lupus erythematosus (SLE).
Disease Hierarchy
DIS2QILP: Chronic cutaneous lupus erythematosus
DISMK3AH: Discoid lupus erythematosus
ICD Code
ICD-11
ICD-11: EB51.0
ICD-10
ICD-10: L93.2
ICD-9
ICD-9: 695.4
Expand ICD-11
'EB51.0
Expand ICD-10
'L93.2
Expand ICD-9
695.4
Disease Identifiers
MONDO ID
MONDO_0019558
UMLS CUI
C5574816
MedGen ID
1811126
HPO ID
HP:0007417
Orphanet ID
90281
SNOMED CT ID
200938002

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 3 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
CC-930 DMHVEGJ Phase 2 Small molecular drug [1]
Daxdilimab DM5BV5H Phase 2 Monoclonal antibody [2]
AMG 811 DMEIMBP Phase 1 NA [3]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1 ClinicalTrials.gov (NCT01203943) A Study to Characterize the Safety, PK and Biological Activity of CC-930 in Idiopathic Pulmonary Fibrosis (IPF). U.S. National Institutes of Health.
2 ClinicalTrials.gov (NCT05591222) A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Trial to Investigate the Efficacy and Safety of Daxdilimab Subcutaneous Injection in Reducing Disease Activity in Adult Participants With Moderate-to-Severe Primary Discoid Lupus Erythematosus. U.S.National Institutes of Health.
3 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028077)