Details of Disease | DrugMAP

General Information of Disease (ID: DISMSLXN)

Disease Name	Hearing loss, autosomal recessive 108
Synonyms	autosomal recessive nonsyndromic deafness 108; deafness, autosomal recessive 108; DFNB108
Disease Hierarchy	DIS8G9R9: Hearing loss, autosomal recessive DISMSLXN: Hearing loss, autosomal recessive 108
Disease Identifiers	MONDO ID MONDO_0033200 UMLS CUI C4539997 OMIM ID 617654 MedGen ID 1627841

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 2 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
ROR1	TTDEJAU	Moderate	Autosomal recessive	[1]
ROR1	TTDEJAU	Strong	Biomarker	[1]
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This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
ROR1	OTEUYEW6	Moderate	Autosomal recessive	[1]
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References

1	ROR1 is essential for proper innervation of auditory hair cells and hearing in humans and mice. Proc Natl Acad Sci U S A. 2016 May 24;113(21):5993-8. doi: 10.1073/pnas.1522512113. Epub 2016 May 9.