Details of Disease

General Information of Disease (ID: DISN73RD)

• Disease Name: Varicella
• Synonyms: chicken pox; chicken pox infection; chickenpox; Varicella; varicella
• Disease Class: 1E90: Varicella
• Definition: A contagious childhood disorder caused by the varicella zoster virus. It is transmitted via respiratory secretions and contact with chickenpox blister contents. It presents with a vesicular skin rash, usually associated with fever, headache, and myalgias. The pruritic fluid-filled vesicles occur 10-21 days after exposure and last for 3-4 days. An additional 3-4 days of malaise follows before the affected individual feels better. An individual is contagious 1-2 days prior to the appearance of the blisters until all blisters are crusted over. Generally, healthy individuals recover without complications.
• Disease Hierarchy:
  DISV4VFZ: Vesiculobullous skin disease
  DIS7U38D: Varicella zoster virus infection
  DISFDJN8: Skin disorder caused by infection
  DISN73RD: Varicella
• ICD Code: ICD-11: ICD-11: 1E90
• Disease Identifiers:
  MONDO ID: MONDO_0005700
  MESH ID: D002644
  UMLS CUI: C0008049
  MedGen ID: 2995
  SNOMED CT ID: 38907003

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 2 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Aciclovir	DMYLOVR	Approved	Small molecular drug	[1]
Valaciclovir	DMHKS94	Approved	Small molecular drug	[2]

This Disease is Treated as An Indication in 2 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
GSK4178116A	DM5ETIR	Phase 2	Vaccine	[3]
GSK4406371A	DMGKKR9	Phase 2	Vaccine	[3]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] Neonatal varicella. Arch Dis Child. 2023 Oct 31:archdischild-2022-324820.
• [2] Chickenpox. BMJ Clin Evid. 2011 Apr 11;2011:0912.
• [3] Clinical pipeline report, company report or official report of GlaxoSmithKline