Details of Disease

Disease Name

Primary biliary cirrhosis

Disease Class

DB96: Autoimmune liver disease

Disease Hierarchy

DIS01GPL: Grass pollen hypersensitivity

DISOUHB2: Primary biliary cirrhosis

ICD-11

ICD-11: DB96.1

ICD-10

ICD-10: K74.3

ICD-9

ICD-9: 571.6

Expand ICD-11

'DB96.1

Expand ICD-10

'K74.3

Expand ICD-9

571.6

Disease Identifiers

MONDO ID

MONDO_0005155

MESH ID

D008103

UMLS CUI

C0023890

MedGen ID

7368

HPO ID

HP:0001394

SNOMED CT ID

19943007

General Information of Disease (ID: DISOUHB2)

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 1 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Ursodeoxycholic acid	DMCUT21	Approved	Small molecular drug	[1]
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This Disease is Treated as An Indication in 3 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Autologous chondrocyte implantation	DM57PYM	Phase 3	NA	[2]
LUM001	DMQZXDW	Phase 2	NA	[3]
NGM 282	DMB8PDM	Phase 2	NA	[4]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7104).
2	ClinicalTrials.gov (NCT01066702) Confirmatory Study of NeoCart in Knee Cartilage Repair. U.S. National Institutes of Health.
3	ClinicalTrials.gov (NCT02321306) An Open-label Study to Evaluate the Long-term Safety and Tolerability of LUM001 in Patients With Primary Biliary Cirrhosis. U.S. National Institutes of Health.
4	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)