Details of Disease

General Information of Disease (ID: DISPBWVK)

Disease Name Type IV hypersensitivity disease
Synonyms
immunoproliferative disease; hypersensitivity reaction type IV disease; type IV hypersensitivity reaction; type IV hypersensitivity; type 4 hypersensitivity reaction; disorder of type IV hypersensitivity; delayed-type hypersensitivity response; delayed-type hypersensitivity; delayed hypersensitivity reaction; DTH
Definition A disease that has its basis in the disruption of type IV hypersensitivity.|We make this equivalent with the UMLS concept for the reaction
Disease Hierarchy
DISWD40R: Disease
DISEDL2I: Hypersensitivity
DISPBWVK: Type IV hypersensitivity disease
Disease Identifiers
MONDO ID
MONDO_0002459
MESH ID
D006968
UMLS CUI
C0020522
MedGen ID
9371
SNOMED CT ID
28031001

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 4 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
CXCR3 TT1UCIJ Strong Biomarker [1]
GATA3 TT45KOB Strong Biomarker [2]
HLA-DQA1 TTU2I3J Strong Biomarker [3]
IL17A TTG0MT6 Strong Biomarker [4]
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This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
HLA-DQB1 OTVVI3UI Strong Biomarker [3]
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References

1 CXCR3 is required for migration to dermal inflammation by normal and in vivo activated T cells: differential requirements by CD4 and CD8 memory subsets.Eur J Immunol. 2005 Jun;35(6):1702-11. doi: 10.1002/eji.200425885.
2 GATA-3 expression in the development of anterior chamber associated immune deviation.Chin Med J (Engl). 2005 Dec 5;118(23):2000-4.
3 Two-domain MHC class II molecules form stable complexes with myelin basic protein 69-89 peptide that detect and inhibit rat encephalitogenic T cells and treat experimental autoimmune encephalomyelitis.J Immunol. 1998 Dec 1;161(11):5987-96.
4 Suppression of experimental autoimmune uveoretinitis by Anti-IL-17 antibody.Curr Eye Res. 2009 Apr;34(4):297-303. doi: 10.1080/02713680902741696.