Details of Disease

Disease Name

Menopause symptom

Disease Class

GA30: Menopausal disorder

Disease Hierarchy

DIS01GPL: Grass pollen hypersensitivity

DISQ562P: Menopause symptom

ICD-11

ICD-11: GA30.0

Expand ICD-10

F30,F31,F32,F33,F34,F35,F36,F37,F38,F39,F32,F33,N95

Expand ICD-9

296,296.2,296.3,627.2

General Information of Disease (ID: DISQ562P)

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 4 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Cenestin	DMXQS7K	Approved	Small molecular drug	[1]
Conjugated Estrogens	DMLT0E1	Approved	Small molecular drug	[2]
Desvenlafaxine	DMHD4PE	Approved	Small molecular drug	[3]
Estrogen	DMGY0UT	Approved	NA	[1]
------------------------------------------------------------------------------------

This Disease is Treated as An Indication in 2 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Genistein	DM0JETC	Phase 2/3	Small molecular drug	[4]
VG-101	DMAN21O	Phase 1/2	NA	[5]
------------------------------------------------------------------------------------

This Disease is Treated as An Indication in 1 Discontinued Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Chlorotrianisene	DMSV2WZ	Withdrawn from market	Small molecular drug	[6]
------------------------------------------------------------------------------------

This Disease is Treated as An Indication in 1 Investigative Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
TSERaM	DM6JF7T	Investigative	NA	[7]
------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2	ClinicalTrials.gov (NCT01613170) Premarin Versus Toviaz for Treatment of Overactive Bladder. U.S. National Institutes of Health.
3	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7158).
4	ClinicalTrials.gov (NCT00355953) Vascular and Skeletal Protective Effects of Genistein in Postmenopausal Women. U.S. National Institutes of Health.
5	ClinicalTrials.gov (NCT00453089) VG101 Phase I/II to Treat Vulvar and Vaginal Atrophy in Post-Menopausal Women. U.S. National Institutes of Health.
6	FDA Approved Drug Products from FDA Official Website. 2008. Application Number: (ANDA) 017675.
7	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 620).